LABOTEST-BB LT00772280
SULFAPHENAZOLE
CAS: 526-08-9
Molecular Formula: C15H14N4O2S
LABOTEST-BB LT00772280 - Names and Identifiers
| Name | SULFAPHENAZOLE |
| Synonyms | Orisul Orisulf Paidazolo SULFAPHENAZOLE LABOTEST-BB LT00772280 N1-(1-Phenylpyrazol-5-yl)sulfanilamide n'-(1-phenylpyrazol-5-yl)sulfanilamide n(sup1)-(1-phenylpyrazol-5-yl)sulfanilamide 4-AMINO-N-(1-PHENYL-1H-PYRAZOL-5-YL)BENZENESULFONAMIDE |
| CAS | 526-08-9 |
| EINECS | 208-384-3 |
LABOTEST-BB LT00772280 - Physico-chemical Properties
| Molecular Formula | C15H14N4O2S |
| Molar Mass | 314.36 |
| Density | 1.39 |
| Melting Point | 179-183 °C |
| Boling Point | 541.9±56.0 °C(Predicted) |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | white to light yellow |
| pKa | pKa 5.71(H2O t = 25 I = 0.05) (Uncertain) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.6440 (estimate) |
| Physical and Chemical Properties | Bioactive Sulfaphenazole is a specific inhibitor of CYP2C9, which inhibits CYP2C9-mediated linoleic acid atherosclerosis and pro-inflammatory effects (increasing oxidative stress and activation of AP-1) and is used as an antibacterial agent. |
| Use | Use Sulfadibenzazole is a specific inhibitor of CYP2C9, which can block CYP2C9-mediated linoleic acid-induced atherosclerosis and pro-inflammatory effects (increasing oxidative stress and activating AP-1). Play the role of antibacterial and antibacterial. Sulfamepyrazole was used as a positive control to inhibit cytochrome P450 2C9 (cyp2c9) to quantify the inhibitory effect of Rhodiola rosea. It was also used as a cytochrome P450 2C9 (cyp2c9) inhibitor in endothelial cells and microsomal preparations. |
LABOTEST-BB LT00772280 - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 2 |
| RTECS | DA9520000 |
| HS Code | 29339900 |
| Toxicity | LD50 orally in mice: 5800 mg/kg (Seki) |
LABOTEST-BB LT00772280 - Reference
| Reference Show more | 1. Wang Chengyu, Li Dengke, Quan Zhengyang, Hu Ying also, Sun Zhenxiao. Study on hepatotoxicity and related components of Polygonum multiflorum based on cytochrome oxidase CYP2D6 [J]. Pharmacovigilance in China, 2021,18(03):220-227 239. 2. Chen Rui, Zhou Wei, Zhang Li, Zhu Gaogao, Huang Jing, Tang Lei. In vitro inhibition of five common Cytochrome P_(450) enzymes in human liver microsomes by bevacizumab acid A [J]. China Pharmacy, 2021,32(02):195-200. 3. Hu et al Ying-huan [IF = 3.5]. "Inhibition of CYP3A4 senses aloe-emodin induced hepatocyte injury." Toxicol In Vitro. 2021 Dec;:105276 |
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Product Name: Sulfaphenazole Visit Supplier Webpage Request for quotationCAS: 526-08-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Multiple SpecificationsSpot supply
Product Name: Sulfaphenazole Visit Supplier Webpage Request for quotationCAS: 526-08-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Sulfaphenazole Visit Supplier Webpage Request for quotationCAS: 526-08-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple Specifications
Product Name: Sulfaphenazole Visit Supplier Webpage Request for quotationCAS: 526-08-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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